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Faculty member

Arafa Kassem Musa

Associate Professor

Arafa Kassem Musa
5532
akmusa@ju.edu.sa
- College Of Pharmacy
College
College Of Pharmacy
كلية الصيدلة
Department
ArafaMusa20096848
ArafaMusa20096848
Researches
54
54
Page Visits
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Current courses

Code Year Course Name
RPHG 476 Applied Pharmacognosy
RPHG 346 Pharmacognosy II
RPHG 496 Alternative Medicine

Recent courses

Code Year Course Name
RPCL 228 Introduction to Pharmacy Profession
RPHG 346 Pharmacognosy II
RPCL 228 Introduction to Pharmacy Profession
RPHG 496 Alternative Medicine
RPHG 476 Applied Pharmacognosy
RPHG 496 Alternative Medicine
RPHG 346 Pharmacognosy II
RPHG 496 Alternative Medicine
RPHG 476 Applied Pharmacognosy
RPHG 346 Pharmacognosy II
RPHG 476 Applied Pharmacognosy

Fm researches

Last Researches

Phenyltriazole-based sulfonamides: novel dual-target agents against MRSA biofilms and resistant pathogens
Arafa Kassem A Musa
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Design and construction of novel pyridine-pyrimidine hybrids as selective COX-2 suppressors: anti-inflammatory potential, ulcerogenic profile, molecular modeling and ADME/Tox studies
Arafa Kassem A Musa
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Theaflavin alleviates cisplatin-induced nephrotoxicity: Targeting SIRT1/p53/FOXO3a/Nrf2 signaling and the NF-kB inflammatory cascade
Arafa Kassem A Musa
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fm info

Researches

Phenyltriazole-based sulfonamides: novel dual-target agents against MRSA biofilms and resistant pathogens
Arafa Kassem A Musa
Read more
Design and construction of novel pyridine-pyrimidine hybrids as selective COX-2 suppressors: anti-inflammatory potential, ulcerogenic profile, molecular modeling and ADME/Tox studies
Arafa Kassem A Musa
Read more
Theaflavin alleviates cisplatin-induced nephrotoxicity: Targeting SIRT1/p53/FOXO3a/Nrf2 signaling and the NF-kB inflammatory cascade
Arafa Kassem A Musa
Read more
Optimizing encapsulation of garlic and cinnamon essential oils in silver nanoparticles for enhanced antifungal activity against Botrytis cinerea pathogenic disease
Arafa Kassem A Musa
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Enzymes in Neurodegenerative Disorders: Mechanism and Therapeutic Potentials - Role of Enzymes in Huntington’s Disease
Arafa Kassem A Musa
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Alleviation of Copper-Induced Hepatotoxicity by Bergenin: Diminution of Oxidative Stress, Inflammation, and Apoptosis via Targeting SIRT1/FOXO3a/NF-κB Axes and p38 MAPK Signaling
Arafa Kassem A Musa
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Prominent antidiabetic and anticancer investigation of Scrophularia deserti extract: Integration of experimental and computational approaches
Arafa Kassem A Musa
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Design and construction of novel pyridinepyrimidine hybrids as selective COX-2 suppressors: anti-inflammatory potential, ulcerogenic profile, molecular modeling and ADME/Tox studies
Arafa Kassem A Musa
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Curcumin: a bioactive compound with molecular targets for human malignancies Save Related Papers Chat with paper
Arafa Kassem A Musa
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Cytotoxic and Antioxidant Potential of Launaea mucronata Forssk Essential Oil Growing in Northern Saudi Arabia
Arafa Kassem A Musa
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Introducing of novel class of pyrano[2,3-c]pyrazole-5-carbonitrile analogs with potent antimicrobial activity, DNA gyrase inhibition, and prominent pharmacokinetic and CNS toxicity profiles supported by molecular dynamic simulation
Arafa Kassem A Musa
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Halogenated class of oximes as a new class of monoamine oxidase-B inhibitors for the treatment of Parkinson’s disease: Synthesis, biochemistry, and molecular dynamics study
Arafa Kassem A Musa
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The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations
Arafa Kassem A Musa
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Phthalazone tethered 1,2,3-triazole conjugates: In silico molecular docking studies, synthesis, in vitro antiproliferative, and kinase inhibitory activities
Arafa Kassem A Musa
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Phenylpyrazolone-1,2,3-triazole Hybrids as Potent Antiviral Agents with Promising SARS-CoV-2 Main Protease Inhibition Potential
Arafa Kassem A Musa
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Phenanthroindolizidine Alkaloids Secondary Metabolites Diversity in Medicinally Viable Plants of the Genus Tylophora
Arafa Kassem A Musa
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Design, Synthesis, Molecular Modeling, and Anticancer Evaluation of New VEGFR-2 Inhibitors Based on the Indolin-2-One Scaffold
Arafa Kassem A Musa
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Screening and Molecular Docking of Bioactive Metabolites of the Red Sea Sponge Callyspongia siphonella as Potential Antimicrobial Agents
Arafa Kassem A Musa
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Wound Healing and Antioxidant Properties of Launaea procumbens Supported by Metabolomic Profiling and Molecular Docking
Arafa Kassem A Musa
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Extensive Study of DFT-Quantum Calculations Based QSAR Modeling of Fused 1,2,4-Triazine Derivatives Revealed Potent CYP1A1 Inhibitors
Arafa Kassem A Musa
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In Vitro Anti-Proliferative, and Kinase Inhibitory Activity of Phenanthroindolizidine Alkaloids Isolated from Tylophora indica
Arafa Kassem A Musa
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New Sulfamethoxazole Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors: Design, Synthesis, Cytotoxic Activity and Molecular Modeling
Arafa Kassem A Musa
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LC/MS Profiling and Gold Nanoparticle Formulation of Major Metabolites from Origanum majorana as Antibacterial and Antioxidant Potentialities
Arafa Kassem A Musa
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LC/MS Profiling and Gold Nanoparticle Formulation of Major Metabolites from Origanum majorana as Antibacterial and Antioxidant Potentialities
Arafa Kassem A Musa
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Chitosan Silver and Gold Nanoparticle Formation Using Endophytic Fungi as Powerful Antimicrobial and Anti-Biofilm Potentialities
Arafa Kassem A Musa
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Development of bromo-and fluoro-based α, β-unsaturated ketones as highly potent MAO-B inhibitors for the treatment of Parkinson's disease
Arafa Kassem A Musa
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Design, synthesis, and biological evaluation of novel pyrido-dipyrimidines as dual topoisomerase II/FLT3 inhibitors in leukemia cells
Arafa Kassem A Musa
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Phytotoxic effects of Acacia saligna dry leachates on germination, seedling growth, photosynthetic performance, and gene expression of economically important crops
Arafa Kassem A Musa
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Docking Study, Synthesis, and Anti-Inflammatory Potential of Some New Pyridopyrimidine-Derived Compounds
Arafa Kassem A Musa
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Botanical description, bioactivity guided isolation and in silico mode of action of anti-diabetic constituents of Pterocarpus dalbergioides flowers
Arafa Kassem A Musa
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Volatile Constituents of Cistanche tubulosa and Their Antioxidant and Antimicrobial Potentials
Arafa Kassem A Musa
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Targeting tumor cells with pyrazolo[3,4-d] pyrimidine scaffold: A literature review on synthetic approaches, structure activity relationship, structural and target-based mechanisms
Arafa Kassem A Musa
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EGFR and COX-2 Dual Inhibitor: The Design, Synthesis, and Biological Evaluation of Novel Chalcones
Arafa Kassem A Musa
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Docking Study, Synthesis, and Anti-Inflammatory Potential of Some New Pyridopyrimidine-Derived Compounds
Arafa Kassem A Musa
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Development and Greenness Assessment of HPLC Method for Studying the Pharmacokinetics of Co-Administered Metformin and Papaya Extract
Arafa Kassem A Musa
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Gene Therapy Approach with an Emphasis on Growth Factors: Theoretical and Clinical Outcomes in Neurodegenerative Diseases
Arafa Kassem A Musa
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Formulation of Genistein-HP β Cyclodextrin-Poloxamer 188 Ternary Inclusion Complex: Solubility to Cytotoxicity Assessment.
Arafa Kassem A Musa
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An In Vitro and In Silico Study of the Enhanced Antiproliferative and Pro-Oxidant Potential of Olea europaea L. cv. Arbosana Leaf Extract via Elastic Nanovesicles (Spanlastics)
Arafa Kassem A Musa
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Formulation of ternary genistein β-cyclodextrin inclusion complex: In vitro characterization and cytotoxicity assessment using breast cancer cell line
Arafa Kassem A Musa
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An Agathokakological Tale of Δ9-THC: Exploration of Possible Biological Targets
Arafa Kassem A Musa
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Strawberry and Ginger Silver Nanoparticles as Potential Inhibitors for SARS-CoV-2 Assisted by In Silico Modeling and Metabolic Profiling
Arafa Kassem A Musa
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Cytotoxic Potential, Metabolic Profiling, and Liposomes of Coscinoderma sp. Crude Extract Supported by in silico Analysis
Arafa Kassem A Musa
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Olive Oil/Pluronic Oleogels for Skin Delivery of Quercetin: In Vitro Characterization and Ex Vivo Skin Permeability
Arafa Kassem A Musa
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Chemical characteristics and targeted encapsulated Cordia myxa fruits extracts nanoparticles for antioxidant and cytotoxicity potentials
Arafa Kassem A Musa
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Phytochemistry, Pharmacological Potency, and Potential Toxicity of Myoporum spp.
Arafa Kassem A Musa
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Novel Phenolic Compounds as Potential Dual EGFR and COX-2 Inhibitors: Design, Semisynthesis, in vitro Biological Evaluation and in silico Insights
Arafa Kassem A Musa
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Potential Anticancer Lipoxygenase Inhibitors from the Red Sea-Derived Brown Algae Sargassum cinereum: An In-Silico-Supported In-Vitro Study
Arafa Kassem A Musa
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Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations
Arafa Kassem A Musa
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In silico study, protein kinase inhibition and antiproliferative potential of flavonoids isolated from Bassia eriophora (Schrad.) growing in KSA
Arafa Kassem A Musa
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Enhanced full-thickness wound healing via Sophora gibbosa extract delivery based on a chitosan/gelatin dressing incorporating microemulsion
Arafa Kassem A Musa
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Insights Studies for Certain Natural FDA Approved Polyphenolics and Repurposing for COVID-19
Arafa Kassem A Musa
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Design, Synthesis, and Biological Evaluation of Pyridazinones Containing the (2-Fluorophenyl) Piperazine Moiety as Selective MAO-B Inhibitors
Arafa Kassem A Musa
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Projects

Discovery of Heterocyclic Potent Anticancer and Antimicrobial Agents Targeting Cell Membrane and Cellular Enzymes
2024 - 2025
Novel Quinolines and/or Heterocyclic Scaffolds as a New Approach for Cancer Treatment
2022 - 2023

COVID-19 infection is now considered one of the leading causes of human death. As an attempt towards the discovery of novel medications for the COVID-19 pandemic, nineteen novel compounds containing 1,2,3-triazole side chains linked to phenylpyrazolone scaffold and terminal lipophilic aryl parts with prominent substituent functionalities were designed and synthesized via a click reaction based on our previous work. The novel compounds were assessed using an in vitro effect on the growth of SARS-CoV-2 virus-infested Vero cells with different compound concentrations: 1 and 10 μM.

Crafting Resilient Antibiotics: Rational Design, Biotargeting, and Synthesis of Phenylthiazoles analogs with application nanoformulation to Combat Multidrug-Resistant Pathogens
2024 - 2025

Education

Ph.D.
Al-Azhar University (Egypt) and Ludwig-Maximillian, Munich, Germany - College of Pharmacy
2011 - 2007
BA
Al-Azhar University, Cairo, Egypt - College of Pharmacy
1998 - 1993
M.A.
Al-Azhar University - College of Pharmacy
2005 - 2001

Experience

Associate Professor
College of Pharmacy - Jouf University
2023 - 2024

Teaching, scientific research

Assistant Professor
College of Pharmacy - Jouf University
2013 - 2023

Teaching and Scientific Research

Rapporteur of many college committees, the most important of which is the Training and Alumni Committee
College of Pharmacy - Jouf University
2014 - 2024
Head of Pharmacognosy Dept., College of Pharmacy, Jouf University
College of Pharmacy - Jouf University
2014 - 2021

Teaching, scientific research, and management of the pharmacognosy department

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