SAYED AHMED ELMANSI IMAN

Background and Objective: Doxorubicin is an antineoplastic drug used in the treatment of DEN-induced HCC in male rats, but it causes cardiomyocyte toxicity. It is possible that the administration of tomato juice during DOX therapy may be beneficial. The present work explored that ingestion of tomato juice by DEN-induced HCC rats daily for 4 weeks alleviated DOX-induced cardiotoxicity.

this study aimed to observe the toxicity of cyclosporine on liver and spleen
tissues and evaluate the ameliorative effects of alpha-lipoic acid (?-LA) on
cyclosporine adverse effects. Alpha-lipoic acid (?-LA), is synthesized in
animal and plant tissues and has protective effects in a variety of disease

Hepatic encephalopathy (HE) is neurological disarray manifested as a sequel to chronic and acute liver failure (ALF). A potentially fatal consequence of ALF is brain edema with concomitant astrocyte enlargement. The present study aims to outline the role of astrocytes in acute HE and shedding light on the most critical mechanisms driving this role