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محمد حسن الكومي

أستاذ مشارك

محمد حسن الكومي
mhalkomy@ju.edu.sa
الصيدلانيات - كلية الصيدلة
الكلية
College Of Pharmacy
كلية الصيدلة
القسم
MOHAMMEDALKOMY20214467
MOHAMMEDALKOMY20214467
الأبحاث
45
45
زيارات الصفحة
No view count available

المقرارت الحالية

المقرارت الاخيرة

Fm researches

آخر الأبحاث

Crafting cationic lecithmer nanocomposites as promising wagons for brain targeting of cinnamaldehyde: Accentuated neuroprotection via downregulation of Aβ1-42/p-tau crosstalk
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Intranasal trimethyl chitosan-coated emulsomes containing tizanidine as brain-targeted therapy in spasticity: formulation, optimization, and pharmacokinetic assessment
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Brain targeting of venlafaxine via intranasal transbilosomes thermogel for improved management of depressive disorder
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY

fm info

الأبحاث

Crafting cationic lecithmer nanocomposites as promising wagons for brain targeting of cinnamaldehyde: Accentuated neuroprotection via downregulation of Aβ1-42/p-tau crosstalk
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Intranasal trimethyl chitosan-coated emulsomes containing tizanidine as brain-targeted therapy in spasticity: formulation, optimization, and pharmacokinetic assessment
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Brain targeting of venlafaxine via intranasal transbilosomes thermogel for improved management of depressive disorder
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Repurposing celecoxib for colorectal cancer targeting via pH-triggered ultra-elastic nanovesicles: Pronounced efficacy through up-regulation of Wnt/β-catenin pathway in DMH-induced tumorigenesis
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Polymeric Nanoparticles for Delivery of Natural Bioactive Agents: Recent Advances and Challenges
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Novel nasal niosomes loaded with lacosamide and coated with chitosan: A possible pathway to target the brain to control partial-onset seizures
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Intranasal Nanotransferosomal Gel for Quercetin Brain Targeting: II. Antidepressant Effect in an Experimental Animal Model
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Intranasal Nanotransferosomal Gel for Quercetin Brain Targeting: I. Optimization, Characterization, Brain Localization, and Cytotoxic Studies
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Oral sildenafil citrate: a potential approach for improvement of endometrial thickness and treatment of unexplained infertility in women
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Exploring the potential of quercetin/aspirin-loaded chitosan nanoparticles coated with Eudragit L100 in the treatment of induced-colorectal cancer in rats
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Formulation and optimization of Naringin polymeric nanoparticles: Optimization to in vivo evaluation
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Transfersomal nanovesicles for nose-to-brain delivery of ofloxacin for better management of bacterial meningitis: Formulation, optimization by Box-Behnken design, characterization and in vivo pharmacokinetic study
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Development and machine-learning optimization of mucoadhesive nanostructured lipid carriers loaded with fluconazole for treatment of oral candidiasis
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Development, optimization, and in vitro/in vivo characterization of enhanced lipid nanoparticles for ocular delivery of ofloxacin: the influence of pegylation and chitosan coating
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Assessment of Ketamine Adult Anesthetic Doses in Pediatrics Using Pharmacokinetic Modeling and Simulations
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Development and assessment of phospholipid-based luteolin-loaded lipid nanocapsules for skin delivery
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Chitosan on the surface of nanoparticles for enhanced drug delivery: A comprehensive review
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Tunable Polymeric Mixed Micellar Nanoassemblies of Lutrol F127/Gelucire 44/14 for Oral Delivery of Praziquantel: A Promising Nanovector against Hymenolepis nana in Experimentally-Infected Rats
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
EthoLeciplex: a new tool for effective cutaneous delivery of minoxidil
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
New Sulfamethoxazole Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors: Design, Synthesis, Cytotoxic Activity and Molecular Modeling
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Bilosomes as a promising nanoplatform for oral delivery of an alkaloid nutraceutical: Improved pharmacokinetic profile and snowballed hypoglycemic effect in diabetic rats
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Rutin and Quercetin Counter Doxorubicin-Induced Liver Toxicity in Wistar Rats via Their Modulatory Effects on Inflammation, Oxidative Stress, Apoptosis, and Nrf2
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
LC/MS Profiling and Gold Nanoparticle Formulation of Major Metabolites from Origanum majorana as Antibacterial and Antioxidant Potentialities
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Innovative pulmonary targeting of terbutaline sulfate-laded novasomes for non-invasive tackling of asthma: statistical optimization and comparative in vitro/in vivo evaluation
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Intranasal delivery of granisetron to the brain via nanostructured cubosomes-based in situ gel for improved management of chemotherapy-induced emesis
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Role of ADMA/DDAH-1 and iNOS/eNOS signaling in the gastroprotective effect of tadalafil against indomethacin-induced gastric injury
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Chitosan Silver and Gold Nanoparticle Formation Using Endophytic Fungi as Powerful Antimicrobial and Anti-Biofilm Potentialities
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Impact of highly phospholipid-containing lipid nanocarriers on oral bioavailability and pharmacodynamics performance of genistein
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Arabinoxylan-Carboxymethylcellulose Composite Films for Antibiotic Delivery to Infected Wounds
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Fabrication and In Vitro/In Vivo Appraisal of Metronidazole Intra-Gastric Buoyant Sustained-Release Tablets in Healthy Volunteers
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Surface-Modified Bilosomes Nanogel Bearing a Natural Plant Alkaloid for Safe Management of Rheumatoid Arthritis Inflammation
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Lipid nanocarriers overlaid with chitosan for brain delivery of berberine via the nasal route
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Intratracheally Inhalable Nifedipine-Loaded Chitosan-PLGA Nanocomposites as a Promising Nanoplatform for Lung Targeting: Snowballed Protection via Regulation of TGF-β/β-Catenin Pathway in Bleomycin-Induced Pulmonary Fibrosis
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Development of Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization, In-Vitro, Ex-Vivo, and In-Vivo Evaluation
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Berberine Encapsulated Lecithin–Chitosan Nanoparticles as Innovative Wound Healing Agent in Type II Diabetes
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Antibiotic-Loaded Psyllium Husk Hemicellulose and Gelatin-Based Polymeric Films for Wound Dressing Application
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Physically optimized nano-lipid carriers augment raloxifene and vitamin d oral bioavailability in healthy humans for management of osteoporosis
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Changing the Drug Delivery System: Does it Add to Non-Compliance Ramifications Control? A Simulation Study on the Pharmacokinetics and Pharmacodynamics of Atypical Antipsychotic Drug
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Long-Acting Paliperidone Parenteral Formulations Based on Polycaprolactone Nanoparticles; the Influence of Stabilizer and Chitosan on In Vitro Release, Protein Adsorption, and Cytotoxicity
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
The influence of solid/solvent interfacial interactions on physicochemical and mechanical properties of ofloxacin
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Quality by design (QbD) based development and validation of bioanalytical RP-HPLC method for dapagliflozin: forced degradation and preclinical pharmacokinetic study
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
The Pharmacokinetics of DEX in Infants and Children following Orthotopic Liver Transplantation
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
A novel nanogel loaded with chitosan decorated bilosomes for transdermal delivery of terbutaline sulfate: artificial neural network optimization, in vitro characterization and in vivo evaluation
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Development of novel dapagliflozin loaded solid self-nanoemulsifying oral delivery system: Physiochemical characterization and in vivo antidiabetic activity
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY
Antimicrobial disposition during pediatric continuous renal replacement therapy using an ex vivo model
MOHAMMED HASSAN MOHAMMED EWIS ALKOMY

المشاريع

إمكانات بيرفينيدون كعامل لتقليل مخاطر التليف الرئوي المرتبط بـCOVID19: دراسة عشوائية محكومة
2021 - 2022
التصنيع والتقييم في المختبر/في الجسم الحي لأقراص ميترونيدازول المزدهرة داخل المعدة ذات الإطلاق المستدام لدى متطوعين أصحاء
2021 - 2022
الجسيمات النانوية البوليمرية المحملة بالسينمالدهيد للحماية من مرض الزهايمر
2024 - 2025
علاج التهاب المفاصل الروماتويدي عن طريق البيلوموسومات المعدلة سطحيًا Nanogel التي تحمل قلويد نباتي طبيعي: التوصيف في المختبر والتقييم في الجسم الحي
2021 - 2022
الفعالية العلاجية للسيلدينافيل في علاج العقم غير المبرر لدى النساء: دراسة سريرية عشوائية مستقبلية
2021 - 2022
جسيمات PLGA النانوية المستندة إلى النيفيديبين القابلة للاستنشاق داخل الرغامى كمنصة واعدة لاستهداف الرئة: تقييم في الجسم الحي في نموذج الفئران للتليف الرئوي الناجم عن الباراكوات
2020 - 2021
النانو نيوتراسيوتيكالز: دمج الأدوية المشتقة من الأعشاب مع تقنية النانو
2022 - 2023
إمكانات تعديل سطح الجسيمات النانوية القائمة على الدهون والبوليمرية مع الشيتوزان لتحسين توصيل الأدوية عبر طرق مختلفة: مراجعة
2021 - 2022
التوصيل المشترك لـRiluzole وBerberine الذي يستهدف الدماغ باستخدام جسيمات PLGA-Chitosan النانوية عبر الطريق الأنفي لإدارة التصلب الجانبي الضموري
2024 - 2025
البربارين المحمل بالدهون الصفراوية الغنية بالأملاح (Bilosomes) كحاملات نانوية محتملة لتعزيز التوافر الحيوي عن طريق الفم وتأثير نقص السكر في الدم في الجرذان المصابة بالسكري
2021 - 2022
تطوير وتحسين التعلم الآلي وتوصيف حاملة الدهون ذات البنية النانوية المطلية بالكيتوزان والمحملة بدواء مضاد للفطريات لعلاج داء المبيضات الفموي
2019 - 2020

المؤهلات

بكالوريوس
جامعة القاهرة (فرع بني سويف) - مصر - الصيدلة
2000 - 1995
ماجستير
جامعة القاهرة - مصر - الصيدلة
2005 - 2001
دكتوراه
جامعة أيوا - الولايات المتحدة الأمريكية - الصيدلة
2012 - 2007

الخبرات

أستاذ مساعد
كلية الصيدلة - جامعة بني سويف
2014 - 2018
أستاذ مساعد
كلية الصيدلة - جامعة الجوف
2018 - 2023

الشهادات

زمالة ما بعد الدكتوراه
2013 - 2014
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