منطقة الجوف-جامعة الجوف

As part of ongoing efforts to enhance high-quality research output and support distinguished researchers, and in line with the role of the College of Dentistry at Jouf University in promoting a culture of research and innovation, the College—represented by the Scientific and Research Ethics Committee—has launched the “Researcher’s Impact” Initiative (From Knowledge to Impact). This initiative aims to showcase the most prominent scientific research conducted by faculty members and undergraduate and postgraduate students of the College, thereby contributing to the advancement of research outcomes and strengthening their academic and societal impact.

Within the framework of this initiative, and in recognition and encouragement of research efforts at the College of Dentistry, Jouf University, and in alignment with the objectives of Saudi Vision 2030 to advance the healthcare sector and enhance quality of life, Dr. Saeed bin Saad Al-Qahtani and his research team have achieved a distinguished scientific breakthrough that opens new horizons in the field of regenerative therapies based on tissue repair and preservation.

This achievement is represented by the discovery of a novel mechanism for regulating the behavior of dental pulp stem cells using clinically approved medications. This finding significantly enhances the potential for developing innovative treatments that support the body’s natural self-healing processes rather than relying on tissue removal or replacement, and it aligns with modern directions in regenerative medicine and biological dentistry.

Key findings of the research team include:

- Repurposing safe, clinically approved drugs to regulate the behavior of dental pulp–derived stem cells for the first time. 

- Demonstrating that activation of specific receptors can temporarily slow stem cell proliferation without compromising cell viability. 

- Confirming the ability of stem cells to regain normal activity after cessation of receptor activation. 

- Opening new avenues for therapeutic strategies focused on tissue preservation and regeneration instead of conventional surgical interventions. 

- Presenting a promising scientific model with potential applications in the treatment of nerve and tissue injuries across multiple medical fields.

This achievement reflects the continued commitment of the College of Dentistry at Jouf University to supporting researchers, strengthening applied scientific research, developing human capital, and fostering health innovation. These efforts contribute to achieving the goals of Saudi Vision 2030 in both the healthcare and scientific sectors, while reinforcing the University’s position as a leading center for research and innovation.