The effect of synthesis conditions on the photokilling activity of TiO2 nanostructures

In this study, Titanium dioxide nanostructures were hydrothermally synthesized at different temperatures 130, 170 and 200 C. The structural properties and crystallite size of TiO 2 nanostructures were confirmed through XRD analyses. Moreover, the morphologies were confirmed using TEM analyses. These analyses confirmed the formation of single phase TiO 2 nanostructures. The average crystallite size for the TiO 2 nanostructures synthesized at different hydrothermal temperatures of 130, 170, and 200 C was found to be 11.5 nm, 5.3 nm, and 5 nm, respectively. The impact of changes in these morphologies on the physical characteristics and photokilling activity of cancer cells has been studied. The results showed that the photokilling activity of TiO 2 nanostructures is morphology dependent, with TiO 2 nanowires having the highest activity and nanosheets having the lowest under our experimental conditions.