Design, synthesis, characterization, spectral, chemical analysis, biological evaluation, and molecular docking studies of novel fatty Schiff base ligands and their nickel and mercury complexes

A novel two Fatty Schiff bases ligands of (N-(4-(dimethyl amino) benzylidene Dodecane, heptadecane) hydrazide
and N-(4-(dimethyl amino) benzylidene) dodecane, heptadecan hydrazides and their complexes with Hg and Ni
were synthesized and distinguish by
1
HNMR, FT-IR, spectroscopy, elemental analysis, X-ray Diffractions, thermal
gravimetric analysis, and magnetic moments. In-vitro strains have been used to study their antibacterial prop
erties. The ligands and their metal complexes have been evaluated physiologically by various bacterial and
fungal strains. In the comparison of free ligands with their complexes. The latter were a more potent antibacterial
agent and were more efficient against gram-positive bacteria than gram-negative bacteria. Additionally, in
vestigations using molecular docking have been carried out to assess the ideal binding location and its inhibitory
effect.