Role of Diffusion and T2-Weighted Magnetic Resonance Imaging in Preoperative Assessment of Myometrial Invasion and Staging of Endometrial Carcinoma
Abstract
Aim of Study: The aim of this study is to evaluate the role
of the combined T2WI and DWI in assessment of the depth of
myometrial invasion and staging of endometrial carcinoma at
the preoperative staging.
Patients and Methods: Thirty eight cases were included;
patients referred to Radiology Department of Mansoura University Hospital. There were postmenopausal female patients
with age ranged from 53 to 76 years. All patients were subjected to proper history taking and DWI and T2 MRI. This study
was using a 1.5 T Philips Ingenia MRI scanner.
Results: There is statistically significant difference between myometrial invasion in pateients with endometrial carcinoma by T2 MRI, Dynamic contrast enhanced (DCE) MRI,
DWI MRI regarding the pathology results. Combination of T2
and DWI MRI in assessment of myometrial invasion in patients
with endometrial carcinoma has accuracy, sensitivity, specificity, PPV and NPV of 94.7%, 86.7%, 100%, 100% and 92%
respectively.
Conclusion: DWI is important complementary, and supplementary tools to T2 MRI, not replacing, and thus; It should
be done as routine image modality side by side to conventional
imaging for assessment of myometrial invasion in cases of endometrial carcinoma.