Implant Stability, Bone Graft Loss and Density with Conventional and Mineralized Plasmatic Matrix Bone Graft Preparations - A Randomized Crossover Trial

This study aimed to compare implant stability, bone loss, and bone density using the mineralized plasmatic matrix (MPM) and conventional bone grafting methods. Patients were recruited in a stratified sample and each received 2 implants one at each side of their upper jaws. MPM was randomly placed in the surgical site around one implant on one side while a conventional graft, was placed on the other side in a cross-over design clinical trial. A total of 84 implants were placed in 42 patients. A total of 42 implants utilized conventional grafts (GM1) and a total of 42 implants utilized mineralized plasmatic matrix (GM2). Mean Perio test measurements for implants in the group (GM1) were lower than that for implants in the group (GM2) (1.21±3.0 versus 3.57±2.9). Mean radiographic density at grafted sites with GM2 was: 665.2±236.5 whereas for GM1 it was: 577.8±201.2. Implant stability with MPM in males was significantly higher than females (P<0.001). Bone graft loss with MPM in males was significantly less than females (P=0.001). There were no differences between older and younger patients regarding implant stability, bone loss, and bone density (P>0.05). It is concluded that utilizing MPM in implants may be associated with better implant treatment outcomes of implant stability, bone graft loss, and density when compared to conventional bone grafts. Gender but not age differences may be noticed when comparing implant stability and bone graft loss in implants utilizing MPM.