Computer-Aided Diagnosis for Early Signs of Skin Diseases Using Multi Types Feature Fusion Based on a Hybrid Deep Learning Model

According to medical reports and statistics, skin diseases have millions of victims
worldwide. These diseases might affect the health and life of patients and increase the costs of
healthcare services. Delays in diagnosing such diseases make it difficult to overcome the
consequences of these types of disease. Usually, diagnosis is performed using dermoscopic images,
where specialists utilize certain measures to produce the results. This approach to diagnosis faces
multiple disadvantages, such as overlapping infectious and inflammatory skin diseases and high
levels of visual diversity, obstructing accurate diagnosis. Therefore, this article uses medical image
analysis and artificial intelligence to present an automatic diagnosis system of different skin lesion
categories using dermoscopic images. The addressed diseases are actinic keratoses (solar keratoses),
benign keratosis (BKL), melanocytic nevi (NV), basal cell carcinoma (BCC), dermatofibroma (DF),
melanoma (MEL), and vascular skin lesions (VASC). The proposed system consists of four main
steps: (i) preprocessing the input raw image data and metadata; (ii) feature extraction using six pretrained deep learning models (i.e., VGG19, InceptionV3, ResNet50, DenseNet201, and Xception);
(iii) features concatenation; and (iv) classification/diagnosis using machine learning techniques. The
evaluation results showed an average accuracy, sensitivity, specificity, precision, and disc similarity
coefficient (DSC) of around 99.94%, 91.48%, 98.82%, 97.01%, and 94.00%, respectively.