Assessment of Anti Müllerian Hormone among Women with Polycystic Ovarian Syndrome in Khartoum State

Polycystic ovary syndrome (PCOS) is the most common
cause of chronic anovulation and hyperandrogenism in young
women .POCS is a common endocrinopathy that
accompanied with long term complications. The early
diagnosis of this syndrome can prevent it.
The study aim to assess serum levels of Anti Müllerian
hormone among female with polycystic ovarian syndrome
(PCOS). Sixty clinically diagnosed polycystic ovarian
syndrome (PCOS), were chosen randomly from Reproductive
Health Care Centre in Khartoum State as case group and
thirty apparently healthy individuals as control group. Serum
AMH and fertility hormones were measured by using ELISA
technique. Results were analyzed using Statistical Package
for Social Science (SPSS), computer programmed version 20.
The mean serum levels of AMH was significantly increased
in PCOS female patients when compare with control, (Mean±
SD: 7.6±2.3 ng/ml versus 4.6±0.7 ng/ml), respectively with
(P=< 0.001). There was a significant week positive
correlation between Anti-Müllerian hormone levels and
Luteinizing hormone levels (r=0.239; P= 0.023), and there
was negative correlation between Anti -Müllerian hormone
levels and Body Mass Index (r= -0.267; P= 0.039).
The serum Anti Müllerian Hormone (AMH) measurement
was significantly higher in PCOS patients, which could use
for early marker diagnosis of PCOS patients.