Mechanism-Based Physiological Effects of Piperine: A Review

Piperine is the piperidine alkaloid present in the fruits of Black pepper (Piper nigrum) and long pepper (Piper longum). It is a pungent constituent with remarkable pharmacological properties. Its appropriate use in some pathological conditions of CNS (central nervous system), CVS (cardiovascular system), GIT (gastro intestinal tract) dysfunctions, bone, and various other physiological activities like anti-asthmatic, anti-tumor immunomodulatory, cytoprotective, and hepatoprotective have been reported.