Cerebellar rTMS for Enhancing Coordination in Patients with Multiple Sclerosis: A Narrative Review.

Purpose of Review: Cerebellar repetitive transcranial magnetic stimulation (rTMS) has gained attention as a potential therapeutic intervention for neurological disorders. Recently, there has been growing interest in its use to improve coordination in patients with multiple sclerosis (PwMS). This review aims to examine and discuss the current evidence on the effectiveness of cerebellar rTMS in enhancing motor coordination in individuals with MS. Methods: A comprehensive search of Science Direct, PubMed, and Google Scholar was conducted using keywords such as multiple sclerosis, cerebellar repetitive transcranial magnetic stimulation, coordination, and neurorehabilitation. Articles published from January 2012 to July 2024 were included, and only English-language studies were reviewed. Unpublished manuscripts, conference abstracts, and studies not involving larger scientific investigations were excluded. Results: The findings suggest that cerebellar rTMS, when combined with conventional rehabilitation methods, has the potential to improve coordination in PwMS. However, the available evidence is limited, and larger, more rigorous studies are needed to confirm these findings and establish standardized treatment protocols. Conclusion: Current literature indicates that cerebellar rTMS holds promise as a supplementary intervention for improving coordination in PwMS. Further high-quality trials are required to support its clinical application and to better understand the underlying mechanisms.