Nanomaterials Aiming to Tackle Antibiotic-Resistant Bacteria
Abstract
The global health of humans is seriously affected by the dramatic increases in the
resistance patterns of antimicrobials against virulent bacteria. From the statements released
by the Centers for Disease Control and Prevention about the world entering a post-antibiotic
era, and forecasts about human mortality due to bacterial infection being increased
compared to cancer, the current body of literature indicates that emerging tools such as
nanoparticles can be used against lethal infections caused by bacteria. Furthermore, a different
concept of nanomaterial-based methods can cope with the hindrance faced by common
antimicrobials, such as resistance to antibiotics. The current review focuses on different
approaches to inhibiting bacterial infection using nanoparticles and aiding in the fabrication
of antimicrobial nanotherapeutics by emphasizing the functionality of nanomaterial
surface design and fabrication for antimicrobial cargo.